Speaker:

Rosemary Braun, Associate Professor, Department of Molecular Biosciences, Northwestern University

Title:

The Scale of Life

Abstract:

Living systems exhibit surprising and beautiful self-organization at all scales. At the atomic level, proteins self-assemble into macromolecular complexes. The function of these machines is orchestrated within the cell by regulatory networks, whose activity is in turn dictated by, and coordinated with, the cells environment. This coordination takes place across large spans of space and time: the size and lifetime of organisms as large as the blue whale. Populations and ecosystems of many organisms in turn exhibit remarkable emergent dynamics. Today, advances in single-cell assays enable us to probe the molecular state of every cell in a sample in high-dimensional detail. But is this the correct scale at which to probe living systems? What can we learn from this data, and how can we abstract from the microscopic details to macroscopic phenotypes? In this talk, I will discuss some of our recent work bridging the cell and tissue/organism scales, and discuss some challenges and opportunities for the future.

Speaker Bio:

Rosemary Braun is an Associate Professor of Molecular Biosciences, Applied Mathematics [ESAM], and Physics at Northwestern University. A theoretical physicist by training, she earned her PhD in Physics from the University of Illinois, followed by a Masters in Biostatistics from Johns Hopkins University. She completed her postdoctoral training at the National Cancer Institute (NIH) before joining Northwestern as a faculty member. Today, she works at the intersection of statistics, mathematics, and biology to develop computational tools for analyzing high-dimensional data. In addition to her Northwestern affiliations, she is also Associate Director of the National Institute for Theory and Mathematics in Biology, as well as external faculty of the Santa Fe Institute.

Location:

In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/97015976754
Passcode: NICO25

About the Speaker Series:

Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, data science and network science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.

Related Info